More frequently – indeed, in the majority of cases – the distemper is hardly well developed before it all at once seems to disappear. This peculiarity in the disorder has no doubt given strength to the general faith in specifics for this disease. The animal suddenly so far recovers, or appears to recover, after having been seriously affected, that the inexperienced naturally conclude the dog is either quite well, or evidently so far cured that the efficacy of the remedy administered is not to be disputed. For two or three weeks this deceptive appearance may continue, and in some cases no return of the symptoms may be witnessed; but in the majority of instances the disorder is only dormant, and again starts up as if it had been strengthened by its treacherous repose. The running from the nose comes back in excessive quantities, and either the bowels are singly inflamed, or with them the brain is involved, and fits or diarrhœa, or both united, speedily terminate in death, to arrest which medicine has seldom the power. The loss is on these occasions rarely attributed to distemper, which is thought to have been subdued; but death is commonly set down to fits, or to poison, or to inflammation of the bowels, or to anything else which the imagination of the proprietor may conceive. Hence we get an insight into the value of a large number, and perhaps into all, of the reputed nostrums; and hence it is the more necessary the reader should be made aware of those indications which denote the virus is not eradicated, but only latent as it were, lurking, to spring with greater certainty upon its victim. No one must conclude the distemper is mastered if the dog continues to lose flesh, or if the animal does not rapidly repair the waste consequent upon the earlier stages of the disorder. This tendency to stand still or decline should be carefully observed, and it will seldom deceive. When it is remarked, or even suspected, let the owner be upon his guard. When the distemper is actually overcome, there is a marked disposition to fatten; indeed, so strong is it at this time that, should it not be evident, there can be no doubt as to the cause, especially if a short and slight attack of the disorder has been known to have occurred a little time before. A warning, equally clear to those who will look for and can read it, is to be obtained from the eyes. These may be bright, and even peculiarly transparent; the face have a more animated expression than it displayed during previous health; but if the eyelids are retracted, the membranes will be found red, and the vessels before observed upon will be seen running over the white of the eye. When these things are present, although the coat may be beautifully smooth, the discharge dried up, the shivering gone, the appetite strong, and the spirits boisterous, still there is in the system the seeds of a disease which at no distant period will reappear in its most dangerous form.

Commonly, after the second stage, there is an abatement of the symptoms, without any actual cessation in the discharges. The dog is concluded to be better, and thought to be doing well, but it will not be long before something to excite alarm is witnessed. The eyes or nerves, or lungs or liver, or stomach or intestines may be attacked; or a pustular eruption, or actual mange, or a disposition in the animal to eat its own flesh, or chorœa, or paralysis may appear, and all of these possible varieties require to be separately dwelt upon.

The eyes lose their transparency, the surface is white and opaque, the sight is impaired, and the lids are nearly constantly closed. One or both of the organs of vision may be thus affected; usually the two are simultaneously affected, but seldom with the like intensity. After a few days, and sometimes at the commencement, a small circular depression is to be seen upon the very centre of the eyeball. It is round, and varies in size from that of a pin's head to that of a small pea, but rarely becomes larger. The depression, if nothing be done to check it, deepens till a little shallow pit is exhibited. At other times the hole grows larger and deeper, till the outer covering of the eye is absorbed, or, in common phrase, is eaten through, and the water escapes: this gives relief. If, however, the animal survives, the eye is often perfectly restored, though very frequently a white speck marks the spot which was ulcerated; or the dog is left with weakened eyes, and has a tendency to cataract, which may ultimately render it blind.

The affection of the lungs is denoted by the dog breathing more quickly, and often making a small plaintive or whistling noise during respiration. Though cough is quite as often absent as present; but if present it is usually severe; the pulse is increased, but small and thready, and the appetite may not be impaired. The animal is, however, disinclined to move, if put down at liberty, it always gets into some place where it hopes to be allowed to remain undisturbed. As the symptoms become more intense, the animal constantly sits upon its haunches; but I have not seen it carry the head erect, although authors state this to be one of the indications. There is a desire for fresh air, and the dog will always leave the house, or get to the window or door, if he have an opportunity of so doing. These signs are hardly to be mistaken, but they are easily confirmed. If the ear be applied to the side of a healthy dog's chest, no sound can be detected; but when the lungs are diseased, a very plain noise is readily heard. The presence, therefore, of any murmur, or of anything like air escaping over a dry rough surface, is indicative of disease, and the certainty that the lungs are involved is confirmed.

Dogs of late years have not commonly died of pneumonia during the distemper; but authors speak of the pulmonary form of the disorder as having formerly been a common cause of death. I know it only as a mild variation of the ordinary symptoms. It has not in any case under my observation proved fatal, but has readily yielded to gentle measures, aided by attention to simple diet.

The liver is generally involved. After the termination of a fatal case, this gland is found either soft or more brittle than it ought to be, else it is discovered much enlarged. I never saw it of less than its natural size. Generally it is discolored, mostly of a pale tint; which sometimes exists all over the organ, though the pendulous edges of the lobes are very generally seen of the bright red, suggestive of inflammation. The gall-bladder is always distended with a thin dark-green fluid or impure bile; and a large quantity of the same secretion, but of greater consistency, is distributed over the lining membrane of the anterior intestines. The liver obviously is the cause of the yellow distemper, which is no more than jaundice added to the original and pre-existing disease. Yellow distemper is by writers treated of as a distinct disorder, but I have not yet met with it in that form. When it has come under my notice, it has been no more than one of the many complications which the symptoms are liable to assume. The dog has been ill before his skin became discolored; but the eyes not exhibiting that ordinary discharge which denotes the true character of the affection under which he labored, the distemper was not detected.

Everything concerning distemper is by the generality of the public misunderstood. Most people imagine a dog can have the distemper but once in its life; whereas I had a patient that underwent three distinct attacks in one autumn, that of 1849. The majority of persons who profess an intimate knowledge of the dog will tell you distemper is a disorder peculiar to the young; whereas I know of no age that is exempt from its attack. I have known dogs, high-bred favorites, to be left with men selected because of their supposed familiarity with dog diseases; and these very men have brought to me the animals in the fits which are the wind-up of distemper, yet notwithstanding have been ignorant that their charges had any disease whatever. All the stages and symptoms of ordinary distemper may appear and depart unnoticed; but it is widely different with yellow distemper, for when the yellowness appears, it is so marked that no description of a peculiar symptom need be inserted, since it cannot be overlooked or mistaken. It is attended with excessive debility, and, unless properly combated, is rapidly fatal.

The stomach and intestines are always involved; I have never known a case in which either escaped. The affection of the first is generally shown by sickness during the earliest stage; when also the derangement of the last is denoted by either costiveness or relaxation, the bowels never being perfectly regular; towards the latter stages, or about the third or fourth week, the appetite sometimes becomes enormous; the craving for food is then unnatural, and is so intense that no quantity can appease the hunger. The animal will eat anything; dry bread is taken with avidity, and stones, cinders, straw, and every species of filth are eaten with apparent relish. Such, however, is not always the case, since it is not unusual for the appetite entirely to fail. In either instance the dog rapidly wastes; the flesh seems to melt as it were away, and the change produced by a few days is startling; from having been fat, a thinness which exposes every bone is witnessed in a shorter time than would be supposed possible. At this period vomiting may come on; but when the animal is morbidly ravenous, the stomach does not generally reject its contents. After death I have found it loaded with the most irritating substances, and always acutely inflamed; but no sickness in any instance of this kind has been observed. Vomiting is most generally absent, but the protruded and reddened appearance of the anus will give a clue to the actual condition of the alimentary tube. The stomach is inflamed, not throughout, but in various parts which are in different stages of disease. The pyloric orifice is always more affected than the cardiac; the duodenum, jejunum, and ileum, are inflamed; the cæcum is enlarged, inflamed, and generally impacted. The rectum, however, suffers most severely; it is much reddened and thickened, often to an extraordinary degree. I have known blood to be exuded from the surface of this bowel in such quantities as to destroy the life from actual hemorrhage. In one case, however, a spaniel vomited more than half-a-pint of blood previous to its death, which took place two hours afterwards. A small quantity of blood is ordinarily passed with the fæces toward the latter stage; but in several cases a large amount of pure blood, partly coagulated and unmingled with any fæcal matter, has flowed from the body in a continued stream, to which there will be cessation only as death approaches. The possibility of this occurring will give the reader some idea of the extent and degree in which the bowels are or may be diseased; the symptoms, nevertheless, are not such as would suggest the danger which may be shortly violently exemplified. Irregularity of the intestines may be remarked; but it is not so characterised as to force itself upon the attention. The belly during distemper mostly appears tucked up and small; the intestines, even when costiveness exists, are seldom loaded, but all except the rectum may feel empty. The animal is always bound when the bowels are acutely attacked. The first indication we get of this is often colic. The cries are high and yet full at first; but they only occur at periods, between which the dog seems easy and inclined to sleep; gradually the exclamations become more sharp and short, a quantity of dark-coloured fæces are voided, and relief is for a time experienced; the cries, however, return and become continuous; diarrhœa sets in; the excretions become more and more liquid, by degrees mixed with blood, and of a lighter color. Whenever they are discharged, pain is expressed; but as the animal sinks the cries grow less frequent, till at last the excrements pass involuntarily, and death soon takes place.

The cries, however, are not heard in every instance even of this kind, and the abdomen is not generally sensitive to pressure. When the belly is handled, the dog, by contracting the muscles covering the parts, may denote some small degree of resistance; but I have never known it to struggle during the operation. The curving of the spine, the occasional looks towards the seat of agony, and the efforts made to press or draw the belly upon the ground, will indicate the inflammatory character and the locality of the disease. The pulse does not materially aid the judgment; it becomes quicker and more sharp, but hardly to such an extent that dependence can be placed on its indications. The discharges often cease when the disease, in an acute form, becomes concentrated upon the contents of the abdomen; but the nose is almost always hot and harsh, though in a few cases I have known the part remain cold and moist even to the last. As the close draws near, a very peculiar smell, not absolutely powerful, but more sickly than offensive, is emitted. This odor is consequent upon the fæces, and when it is detected the animal seldom or never survives.

The brain, both Blaine and Youatt speak of as subject to inflammation during the latter stage of distemper. As diseases are peculiarly liable to change, and the appearances assumed at different times are by no means uniform, I may not say those estimable writers never beheld it in such a state; but I am certain I have never seen it in a similar condition; I have found it congested, but far oftener have I discovered it perfectly healthy. One of its coverings (the dura mater) has exhibited a few spots of congestion, but these have been small, each not larger than the head of a moderate sized pin, and in number about ten or twelve; generally they are situated towards the anterior of the cranium (on either side or falx), and near to the crista galli.

The bones forming the roof of the skull have, however, been highly vascular – loaded with dark blood – so that if dried they become of almost a black hue; and without disputing the accuracy of either of the authorities I have mentioned, these appearances to my mind account more satisfactorily for symptoms which no one asserts ever border upon phrenitis. The brain seems to me to be only sympathetically affected, not absolutely involved in this disease. When this is threatened, there is generally some notice given before the fits, succeeded by stupor, are displayed. The eye will sometimes brighten, and the discharge from the nose will cease. This, however, is by no means constant; as it is not rare for both to continue, or even to become more copious; but if one only should remain, the nose is certain to be the part whence the deflexion will issue. No positive dependence, therefore, can be placed upon the discharges from the eye or nose. The eye, nevertheless, is certain to denote that which is on the eve of happening. The pupil may be small; and when it is so, its decrease of size will be marked, and it will have little disposition to enlarge. This, however, is rarely witnessed. Generally the pupil is much enlarged, so much as to conceal the iris, and alter the character of the organ. The eye is moreover retracted, and the dog has a very peculiar expression of mingled pain and stupidity. If the hand be placed upon the head, it will be sensibly hot. No matter how thick the coat may be, the heat will be apparent, and the carotid arteries will sensibly throb. The coat feels dry and is warm, although the animal may be trembling to such a degree as prevents the pulse being counted. Yet the dog seems lively; it is active now, though perhaps a little while ago it was dull; every trivial circumstance now attracts its notice. The appetite is generally ravenous. The dog which only the day before was disinclined to feed, is suddenly disposed to eat more than it ever was known to consume; and it will gnaw and swallow the hardest wood for want of better provender. The amended appetite is mostly one of the symptoms, but it is not invariably witnessed; for occasionally increased activity, and the strange appearance of the eye, are all that indicate the approach of fits. It will not be long, however, before something shall be added which is more definite in its meaning. The dog which was running about suddenly stands still, and begins to smack its lips and champ its jaw. It keeps stationary while doing this, and continues so until a quantity of froth and thick saliva falls from the mouth, drops upon the ground, and then the action ceases. The animal looks around with a vacant stare, evidently not conscious where it is, and starts away, hitting itself perhaps against anything which may oppose its progress. If caught it struggles to get loose, and may even bite the hand which, when conscious, it would perish to defend. Almost immediately, however, it regains its faculties, and then seems quite as well as it appeared to be before the attack came on. It may continue subject to be thus seized for several days; or soon after the first attack, fits or convulsions may start up. During the champing colic may set in, which will only yield when the fits are established. The duration of the champing is not regular; it may be only for a few moments, or for several minutes. The attacks may be no more than one or two in the day, or twenty may occur in a single hour. Generally they remain about three days, but here also there is no rule. I have known them to be present for a week, and also to exist only for a few hours. In these latter cases the condition of the dog is generally not understood. It is taken out for a long walk, or it is indulged with a hearty meal; and in the middle of the one, or shortly after the other, it begins to champ, utters a loud sharp cry, which is suddenly cut short as if the animal was choked. The eyes glare, the mouth is open, and before perfect insensibility ensues, the dog bites at every object near it, then falls down convulsed, the limbs stiffen, the head is drawn back or twisted to one side, the urine and dung are voided; and a slate of unconsciousness, which may cease in a few minutes, or continue for hours, during which the body is in contortions, and the saliva flows freely from the mouth, stretches the poor brute upon the earth. When this is over, the dog recovers as from a trance, being always disposed to ramble, and should its strength permit, will start away at its utmost speed. There is neither to the number nor duration of these fits any limit; they may be few or frequent, and long or short. The second may end the life; or every five minutes, nay oftener, they may occur, and the animal survive for days. Any excitement will bring them on, and the passage of the fæces invariably is accompanied by an attack. Diarrhœa always begins when they commence, and the dog soon loses strength, and lies upon its side unconscious and incapable of motion; the pulse is not to be felt, and gradually without a struggle it expires. Let no man, however, be hasty in saying positively when death has taken place. Often has the life seemed gone, for the heart has been still; but minutes afterwards the animal has gasped, and then began to breathe once more. Death, however, comes at last, for if the dog sinks to such a state, I have never known it to revive.